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Senior Statistical Programmer Consultant Oncology - ClinChoice

Software Engineer

Senior Statistical Programmer Consultant leading end‑to‑end programming for oncology studies, driving regulatory submissions with advanced SAS and R expertise and deep CDISC knowledge.

About the role

Are you interested in working directly for a single sponsor while having the security and additional career opportunities that working for a global CRO can bring? Our team says it’s the best of both worlds...

ClinChoice is searching for a Senior Statistical Programmer Consultant to join one of our clients.

The Senior Statistical Programmer will serve as a senior technical expert responsible for end-to-end programming deliverables, study leadership, and oversight of internal teams and external vendors. This role requires advanced expertise in SAS , familiarity with R , deep knowledge of CDISC standards , and strong experience working on oncology studies and regulatory submissions.

Key Responsibilities

Technical Leadership

Lead programming activities for oncology clinical trials across multiple studies.

Develop, validate, and maintain SDTM and ADaM datasets following CDISC guidelines.

Oversee production of Tables, Listings, and Figures (TLFs) for study reporting and submissions.

Provide SAS programming expertise to support complex data derivations and analyses.

Review and ensure traceability, consistency, and quality of all programming deliverables.

Project & Study Management

Act as programming lead for assigned studies, managing timelines and deliverables.

Work closely with Biostatistics, Data Management, Medical Writing, and Regulatory Affairs.

Coordinate with CROs and external vendors, ensuring compliance, quality, and adherence to client programming standards.

Support integrated analyses including ISS/ISE .

Regulatory & Submission Support

Prepare submission-ready programming outputs and documentation, including define.xml, annotated CRFs, and reviewer guides.

Ensure all programming meets regulatory requirements (FDA, EMA, PMDA).

Contribute to responses for regulatory queries and data requests.

Required Qualifications

Bachelor’s or Master’s degree in Statistics, Computer Science, Mathematics, Life Sciences, or related field.

8–12+ years of statistical programming experience in pharma/biotech or CRO.

Expert-level proficiency in SAS .

Strong understanding of CDISC SDTM and ADaM standards.

Significant experience supporting oncology clinical trials (hematologic or solid tumors).

Experience supporting regulatory submissions and preparing submission-ready outputs.

Excellent communication skills and ability to collaborate cross-functionally.

The Application Process

Once you have submitted your CV, you will receive an acknowledgement that we received it. If you have the requirements we need, you will be invited for phone interview as the first step. Unfortunately, due to the number of applications we receive, we cannot reply to everyone individually if you are not successful.

Skills

software developmentsystem designproblem solving
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CompanyClinChoice
DepartmentEngineering
LocationUnited States
Experience9+ years
Tenurefull-time
LevelSenior

Posted June 22, 2026

Senior Statistical Programmer Consultant Oncology - ClinChoice | OpenTalent