QA Engineer
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use.
By clicking the “Apply” button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda’s Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge.
Job Description
Pursuant to Section 20 C.F.R. 656.10, you are hereby notified that an application for Alien Employment Certification will be filed by Shire Human Genetic Therapies, Inc. for the following job opportunity:
JOB LOCATION: Lexington, MA
POSITION : Principal Automation Engineer
POSITION DESCRIPTION : Shire Human Genetic Therapies, Inc. is seeking a Principal Automation Engineer with the following duties: responsible for operational, project, and strategic support of PLC, DCS, Manufacturing Execution systems, and ancillary data systems used to control and collect data for various building and manufacturing unit operations. Main manufacturing systems include: incubators, bioreactors, chromatography skids, filtration skids, media and buffer preparation vessels, intermediate totes, CIP and caustic distribution skids, COP washers, and autoclaves; provide technical leadership and contribute to the strategic vision of the Automation Engineering group, which supports the equipment and systems in the cGMP manufacturing of commercial and clinical products at Takeda MBO sites; develop and maintain design and fabrication standards for low voltage control panels, instrumentation communication protocols, and overall maintainability of our control hardware by our I&C technicians; accountable for system performance, continuous improvement, system and software platform upgrading, life cycle planning and large-scale and strategic innovation; serve as industry and company recognized subject matter expert on multiple assigned unit operations across multiple platforms; support and lead tasks and activities related to project engineering, including large and transformational projects; serve as consulting to automation engineering and site leadership on major functionality challenges and industry best practices pertaining to design, policies, business processes, goals, and objectives; oversee technical output of full-time engineers, contractors and vendors. Up to 20% domestic and international travel required for project factory acceptance tests and industry meetings and conferences. Up to 20% remote work allowed.
The estimated salary range reflects an anticipated range for this position. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
Posted July 31, 2026